This guideline provides an evidenced-based and patient-centered approach to management of patients with chronic coronary disease, considering social determinants of health and incorporating the principles of shared decision-making and team-based care. Relevant topics include general approaches to treatment decisions, guideline-directed management and therapy to reduce symptoms and future cardiovascular events, decision-making pertaining to revascularization in patients with chronic coronary disease, recommendations for management in special populations, patient follow-up and monitoring, evidence gaps, and areas in need of future research. Where applicable, and based on availability of cost effectiveness data, cost–value recommendations are also provided for clinicians. Many recommendations from previously published guidelines have been updated with new evidence, and new recommendations have been created when supported by published data. Read more…
‘Breakthrough’ Health Supplement Targets Chronic Inflammation and C-Reactive Protein (CRP) Levels
Cardia 7 is a purified Omega 7 supplement that has been clinically shown to reduce C-reactive protein (CRP) levels and chronic inflammation — the best predictor of heart disease
CLEVELAND, OHIO — December 16, 2012 — More than 100 million people in the U.S. who are at risk for heart disease caused by metabolic syndrome and inflammation can now take “Cardia 7”–a purified Omega 7 supplement that has been clinically shown to reduce C-reactive protein (CRP).
The number one killer in the US — heart attacks — is no longer best predicted by cholesterol or triglycerides, but by inflammation which can be measured by C-reactive protein (CRP). It’s estimated that 2,200 people die every day from cardiovascular disease, and half of all heart attack victims who have low cholesterol levels never knew they were at risk.
CRP is a general measure of inflammation in the body and the leading predictor of cardiovascular disease, better than cholesterol and/or triglycerides. For people who have elevated CRP, purified Omega 7 has been clinically shown to reduce CRP by up to 73%. It is also known to decrease insulin resistance, and decrease accumulation of bad fats in the liver — with no side effects.
Chronic inflammation is the best predictor of heart disease and atherosclerosis,” says Michael Roizen, MD, Chief Wellness Officer and Chairman of the Wellness Institute at the Cleveland Clinic.“Chronic inflammation causes swelling and reduction in the diameter of the arteries that can lead to blood clots and accelerate the buildup of plaque and subsequent cardiovascular disease and atherosclerosis. Everyone should get tested to measure their CRP levels, not just to assess risk of heart disease, but there’s new research that shows that elevated levels of C-reactive protein are linked to heart disease, stroke, memory loss, impotence, wrinkling, even Alzheimer’s.”
According to the American Heart Association, people with high CRP are twice as likely to suffer cardiac arrest as those with low levels. “This makes C-reactive protein the most important cardiovascular risk factor we have for men and women over age 50—a more important factor than age, family history, blood pressure, cholesterol, and/or whether you smoke,” says Roizen. “Clearly this merits more trials, and they are already underway.”
The clinical study in humans screened 30 test subjects who took one gel cap per day for a month. On average, taking one gel cap per day, the test lowered LDL cholesterol 11.2%, and for those with elevated baseline inflammation, C-reactive protein was reduced by an average of 73%.
About Michael F. Roizen, MD
Michael F. Roizen, MD, is the Chief Wellness Officer and Chairman of The Wellness Institute at the Cleveland Clinic where he is striving to elevate preventive care and wellness to a driving role in medicine and society by radically improving health and decreasing wellness costs spiritually, physically and economically.
Among Dr. Roizen’s many accomplishments, he co-founded six companies including RealAge sold to Hearst in 2007; co-invented a drug approved by the FDA in April 2008; co-wrote three medical bestsellers and four number one New York Times bestsellers (the YOU series books and RealAge) and formerly served as chair of a Food and Drug Administration advisory committee, as well as editor of six medical journals.
He and Dr. Mehmet Oz co-write the daily “YOU Docs” columns syndicated to 76 newspapers in North America and similar columns in four magazines.
About Cardia 7:
Cardia 7 is manufactured by Tersus Life Sciences. Founded in Cleveland, Ohio in 2010, Tersus was recipient of Therapeutic Discovery Grant for Ground Breaking Medical Research in 2010. Contains Provinal™ Purified Omega 7 fatty acids are purified to express high levels (50% and upwards) of palmitoleic acid (C16:1n7). Future concentrations are projected to be 90% or more. Especially formulated to remove palmitic acid, a saturated fatty acid that has been shown to have toxic effects on pancreatic beta cells (the cells responsible for secreting insulin), leading to a greater chance for insulin resistance and subsequent development of diabetes.
“Atherosclerosis and Purified Omega 7”
In this 4-minute video, Dr. Michael F. Roizen, Chairman of the Wellness Institute of The Cleveland Clinic, talks about atherosclerosis, its causes and consequences: heart disease, stroke, memory loss, impotence, and wrinkling.
Dr. Roizen shares how purified Omega 7 (palmitoleic acid) may potentially help in the fight against diabetes, metabolic syndrome, and atherosclerosis. This is exciting news because Purified Omega 7 “antagonizes” all three because it has been shown to decrease insulin resistance, decrease hepatic fat accumulation, and decrease acute and chronic inflammation – with no known side effects.
To conclude, Dr. Roizen puts all into perspective: Purified Omega 7 could have a huge benefit for our populations as a whole because metabolic syndrome, insulin resistance, and diabetes are big things we need to tackle for us to be more competitive for jobs, and the United States to be more competitive as a society.”
“A medical breakthrough you should know about”
By Drs. Oz & Roizen, the “You Docs” (Excerpted from “Four Medical Breakthroughs you should know about”)
Recently, we were totally blown away by four medical breakthroughs we think you should know about.
Purified Omega 7
The “new” good fat: You’ve already heard plenty about DHA, the great-for-you omega-3 fatty acid in fatty fish and algae or fish-oil capsules. Now, research from Harvard Medical School, the Cleveland Clinic (where Dr. Mike is Chief Wellness Officer) and universities in Hawaii and Japan revealed that [Omega-7 fatty acids found in purified palmitoleic acid have amazing powers too!
Our take: Take 200 milligrams of purified omega-7 in capsule form along with 900 milligrams of DHA daily.
Published in the Houston Chronicle on Friday, July 20, 2012
Image of Dr. Michael Roizen used with permission of Dr. Michael Roizen.
Dr. Michael Roizen is the Author of Real Age, Chairman Chief Wellness Officer of Cleveland Clinic, and Chairman of Scientific Advisory Board of Tersus Pharmaceuticals.
How inflammation and bad cholesterol lead to coronary heart disease
With so much focus on cholesterol, it’s easy to forget that atherosclerosis is an inflammatory disease, a silent killer, that strikes young and old, male, and female, fit and unfit, in the prime of life and peak of health.
To better understand your heart health, you need more than a simple stress test, EKG, or lipid profile…. it’s important to look at the inflammatory markers as well, specifically C-Rreactive Proteins (CRP’s measure inflammation).
Bad cholesterol can build up “inside” your arterial walls
When many people think of atherosclerosis, they think of bad cholesterol accumulating to form plaque on the walls of the arteries themselves. But your arteries are a porous membrane, and if there is inflammation (which can be caused by saturated fats, particularly palmitic acid, which is a favorite of the food industry because it’s inexpensive, tasty, and stable), the low-density lipoproteins (LDL or “bad” cholesterol) are able to enter inside the arterial membranes themselves, and build up inside the arterial walls.
Many people think of plaque building on walls of the arteries themselves. Yet your arteries are a porous membrane, and this video shows how Low-density lipoproteins (LDL or “bad” cholesterol) build up inside the arterial walls.